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Chemical Structure : OSI-296
Catalog No.: PC-49517Not For Human Use, Lab Use Only.
OSI-296 is a potent and selective inhibitor of c-MET and RON kinases with cellular IC50 of 42 and 200 nM, respectively.
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OSI-296 is a potent and selective inhibitor of c-MET and RON kinases with cellular IC50 of 42 and 200 nM, respectively.
OSI-296 shows in vivo efficacy in tumor xenografts models upon oral dosing and is well tolerated.
| M.Wt | 465.31 | |
| Formula | C21H19Cl2FN4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Arno G Steinig, et al. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4381-7.
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