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OXSI-2

Chemical Structure : OXSI-2

CAS No.: 622387-85-3

OXSI-2 (OXSI 2)

Catalog No.: PC-21308Not For Human Use, Lab Use Only.

OXSI-2 is a putative and selective inhibitor of Syk with IC50 of 14 nM, inhibits convulxin-induced platelet functional responses.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

OXSI-2 is a putative and selective inhibitor of Syk with IC50 of 14 nM, inhibits convulxin-induced platelet functional responses.

Physicochemical Properties

M.Wt 353.40
Formula C18H15N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(1-Methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide

References

1. Bhavaraju K, et al. Eur J Pharmacol. 2008 Feb 12;580(3):285-90.

2. Buitrago L, et al. Blood. 2011 Nov 17;118(20):5631-40.

3. Law DA, et al. Blood. 1999;93:2645–2652.

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