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Ogremorphin-1

Chemical Structure : Ogremorphin-1

CAS No.: 352563-21-4

Ogremorphin-1 (OGM1)

Catalog No.: PC-49418Not For Human Use, Lab Use Only.

Ogremorphin-1 (OGM1) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.16 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ogremorphin-1 (OGM1) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.16 uM.
Ogremorphin-1 (OGM1) displays high selectivity against 158 GPCRs in a single point assay using Chem-1 cells.
Ogremorphin-1 (OGM1) could induce abnormal pigmentation during embryonic development, reproducibly induced ventral curvature, wavy notochord, shortened body axis, craniofacial defects, and loss of retinal iridophores.
Ogremorphin-1 (OGM1) disrupts development of neural crest–derived tissues subsequent to the formation of neural crest progenitors, most likely during neural crest migration.

Physicochemical Properties

M.Wt 359.447
Formula C21H17N3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-ethyl-5'-naphthalen-1-ylspiro[1H-indole-3,2'- 3H-1,3,4-thiadiazole]-2-one

References

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