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Ogremorphin

Chemical Structure : Ogremorphin

CAS No.: 294648-66-1

Ogremorphin (OGM8345, OGM)

Catalog No.: PC-49417Not For Human Use, Lab Use Only.

Ogremorphin (OGM, OGM8345) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.71 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Ogremorphin (OGM, OGM8345) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.71 uM.
Ogremorphin (OGM1, OGM8345) was discovered in a chemical genetic zebrafish screen for its ability to perturb neural crest development, which shares basic cell behaviors of migration and invasion with cancer metastasis.
Ogremorphin also inhibited migration and invasive behavior of neural crest–derived human melanoma cells in vitro.

Physicochemical Properties

M.Wt 309.387
Formula C17H15N3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-ethyl-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one

References

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