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Chemical Structure : Olomoucine
Catalog No.: PC-60188Not For Human Use, Lab Use Only.
A potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase.
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A potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase; also inhibits ERK1/MAP kinase (IC50=25 uM); inhibits the starfish oocyte G2/M transition in vivo.
| M.Wt | 298.35 | |
| Formula | C15H18N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Veselý J, et al. Eur J Biochem. 1994 Sep 1;224(2):771-86.
2. Tsou YC, et al. Neurosci Lett. 2016 Aug 15;628:186-93.
3. Fei XF, et al. Brain Res. 2009 Apr 6;1264:85-97.
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