Chemical Structure : Optovin
CAS No.: 348575-88-2
Catalog No.: PC-43222Not For Human Use, Lab Use Only.
Optovin is a reversible photoactivated TRPA1 ligand that can be photoactivated by violet light, enables light-mediated neuronal excitation in treated animals with EC50 of 2 uM at 387 nm (violet), but not to 485 nm (blue), 560 nm (green) or longer wavelengths.
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Optovin is a reversible photoactivated TRPA1 ligand that can be photoactivated by violet light, enables light-mediated neuronal excitation in treated animals with EC50 of 2 uM at 387 nm (violet), but not to 485 nm (blue), 560 nm (green) or longer wavelengths; shows activity on zebrafish, mouse neurons, and recombinant human protein, enables repeated photoactivation of motor behaviors in wild-type zebrafish and mice.
M.Wt | 315.4132 | |
Formula | C15H13N3OS2 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 37 mg/mL |
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Chemical Name/SMILES |
4-Thiazolidinone, 5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo- |
1. Kokel D, et al. Nat Chem Biol. 2013 Apr;9(4):257-63.
2. Lu Y, et al. Anesthesiology. 2016 Dec;125(6):1171-1180.
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