Catalog No.: PC-72211Not For Human Use, Lab Use Only.
Orforglipron hemicalcium hydrate (LY3502970, OWL-833) is a potent, selective, orally active non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) with Ki of 1 nM.
Orforglipron hemicalcium hydrate (LY3502970, OWL-833) is a potent, selective, orally active non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) with Ki of 1 nM.
Orforglipron has low intrinsic efficacy for effector activation and negligible β-arrestin recruitment.
Orforglipron is highly potent, displaying pharmacological bias toward the cAMP second messenger signalling pathway.
Orforglipron exhibits full efficacy at reducing hyperglycaemia in experimental animals.
