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Chemical Structure : Oroxylin A
CAS No.: 480-11-5
Catalog No.: PC-49421Not For Human Use, Lab Use Only.
Oroxylin A is a small molecule transketolase (TKT) inhibitor with SPR KD of 70.7 uM, inhibits hepatocellular carcinoma growth in vitro and in vivo.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $198 | In stock | |
| 100 mg | $398 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Oroxylin A is a small molecule transketolase (TKT) inhibitor with SPR KD of 70.7 uM, inhibits hepatocellular carcinoma growth in vitro and in vivo.
Oroxylin A dose‐dependently decreased TKT protein levels after 48 h treatment in Hep1‐6 mouse hepatoma cells.
Oroxylin A not only inhibited TKT activity and expression, but also activated p53 signalling partially through targeting TKT.
Oroxylin A (0-100 uM) inhibits the growth of patient‐derived organoids.
| M.Wt | 284.267 | |
| Formula | C16H12O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5,7-dihydroxy-6-methoxy-2-phenyl-4H-chromen-4-one |
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1. Jia D, et al. Clin Transl Med. 2022 Nov;12(11):e1095.
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