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Chemical Structure : Osilodrostat
CAS No.: 928134-65-0
Catalog No.: PC-38385Not For Human Use, Lab Use Only.
Osilodrostat (LCI 699) is a potent, orally active inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 of 2.5 and 0.7 nM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $188 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | $548 | In stock | |
| 1 g | Get quote |
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Osilodrostat (LCI 699) is a potent, orally active inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 of 2.5 and 0.7 nM, respectively.
Osilodrostat (LCI 699) reduces serum aldosterone, and has benefit in the treatment of hypertension.
| M.Wt | 227.237 | |
| Formula | C13H10FN3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(R)-4-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)-3-fluorobenzonitrile |
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1. Amar L, et al. Hypertension. 2010 Nov;56(5):831-8.
2. Calhoun DA, et al. Circulation. 2011 Nov 1;124(18):1945-55.
3. Bertagna X, et al. J Clin Endocrinol Metab. 2014 Apr;99(4):1375-83.
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