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Chemical Structure : Otenabant
CAS No.: 686344-29-6
Catalog No.: PC-42723Not For Human Use, Lab Use Only.
Otenabant (CP-945598) is a potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
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Otenabant (CP-945598) is a potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively.
Otenabant (CP-945598) has low affinity (Ki=7600 nM) for human CB2 receptors.
Otenabant (CP-945598) reverses cannabinoid agonist mediated responses, reduces food intake, and increases energy expenditure and fat oxidation in rodents.
| M.Wt | 510.4183 | |
| Formula | C25H25Cl2N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-Piperidinecarboxamide, 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)- |
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1. Fulp A, et al. J Med Chem. 2012 Nov 26;55(22):10022-32.
2. Hadcock JR, et al. Biochem Biophys Res Commun. 2010 Apr 2;394(2):366-71.
3. Aronne LJ, et al. Obesity (Silver Spring). 2011 Jul;19(7):1404-14.
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