Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Otenabant hydrochloride
CAS No.: 686347-12-6
Catalog No.: PC-42724Not For Human Use, Lab Use Only.
A potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $360 | In stock | |
| 250 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively; has low affinity (Ki=7600 nM) for human CB2 receptors; reverses cannabinoid agonist mediated responses, reduces food intake, and increases energy expenditure and fat oxidation in rodents.
Obesity
Phase 3 Discontinued
| M.Wt | 546.8792 | |
| Formula | C25H26Cl3N7O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
DMSO: 1 mg/mL |
|
| Chemical Name/SMILES |
4-Piperidinecarboxamide, 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)-, hydrochloride (1:1) |
|
1. Fulp A, et al. J Med Chem. 2012 Nov 26;55(22):10022-32.
2. Hadcock JR, et al. Biochem Biophys Res Commun. 2010 Apr 2;394(2):366-71.
3. Aronne LJ, et al. Obesity (Silver Spring). 2011 Jul;19(7):1404-14.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
