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Chemical Structure : PARP-1 inhibitor Pip5
CAS No.: 2101323-42-4
Catalog No.: PC-21163Not For Human Use, Lab Use Only.
PARP-1 inhibitor Pip5 is an analog of PARP-1 type I inhibitor AZ0108, inhibits PARP-1 auto-PARylation with IC50 of 4-17 nM, shows similar type I inhibition of PARP-1 but is more cytotoxic than AZ0108.
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PARP-1 inhibitor Pip5 is an analog of PARP-1 type I inhibitor AZ0108, inhibits PARP-1 auto-PARylation with IC50 of 4-17 nM, shows similar type I inhibition of PARP-1 but is more cytotoxic than AZ0108.
| M.Wt | 468.44 | |
| Formula | C23H19F3N6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-(3-(3-(1,1-difluoroethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one |
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1. Moriah R Arnold, et al. Cell Chem Biol. 2022 Dec 15;29(12):1694-1708.e10.
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