You are here:Home-Chemical Inhibitors & Agonists-Cell Cycle/DNA Damage-PARP-PARP10 inhibitor 22
PARP10 inhibitor 22

Chemical Structure : PARP10 inhibitor 22

CAS No.: 2286261-72-9

PARP10 inhibitor 22

Catalog No.: PC-36012Not For Human Use, Lab Use Only.

PARP10 inhibitor 22 is a selective, cell-active inhibitor of PARP10 with IC50 of 1.8 uM, exhibits >10-fold selectivity over a large subset of other PARP family members.

Packing Price Stock Quantity
100 mg Get quote
250 mg Get quote
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PARP10 inhibitor 22 is a selective, cell-active inhibitor of PARP10 with IC50 of 1.8 uM, exhibits >10-fold selectivity over a large subset of other PARP family members.
PARP10 inhibitor 22 inhibits PARP10-dependent MARylation in cells.
PARP10 inhibitor 22 is a useful probe to study PARP10 biology when combined with other PARP10-selective probes with different selectivity profiles.

Physicochemical Properties

M.Wt 306.288
Formula C16H13F3N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-methyl-6-(2-(trifluoromethyl)pyridin-4-yl)-3,4-dihydroisoquinolin-1(2H)-one

References

1. Morgan RK, et al. ACS Med Chem Lett. 2018 Nov 29;10(1):74-79.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: