PD 169316 | p38 MAPK inhibitor | Probechem Biochemicals

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Chemical Structure : PD 169316

CAS No.: 152121-53-4

PD 169316 (PD169316, PD-169316)

Catalog No.: PC-42662Not For Human Use, Lab Use Only.

PD 169316 is a potent, selective p38 MAPK inhibitor with IC50 of 89 nM.

Packing	Price	Stock
1 mg (Free Sample)	$28	In stock
10 mg	$88	In stock
25 mg	$138	In stock
50 mg	$228	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PD 169316 is a potent, selective p38 MAPK inhibitor with IC50 of 89 nM.
PD 169316 displays >100-fold selectivity over ERK, PKA, PKCα.
PD 169316 prevent p38 phosphorylation while promotes the phosphorylation of the pro-survival SAPK/JNK and ERK;

Physicochemical Properties

M.Wt	360.3412
Formula	C20H13FN4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyridine, 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]-

References

1. Gallagher TF, et al. Bioorg Med Chem. 1997 Jan;5(1):49-64.

2. Krishnamoorthy M, et al. J Biochem. 2009 Feb;145(2):177-84.

3. Kozawa O, et al. Cell Signal. 2000 Jul;12(7):447-50.

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PD 169316 (PD169316, PD-169316)

Biological Activity

Physicochemical Properties

References

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