Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : PD173074
CAS No.: 219580-11-7
Catalog No.: PC-42521Not For Human Use, Lab Use Only.
PD173074 is a potent, selective, ATP-competitive FGFR1 inhibitor with IC50 of ~25 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg (Free Sample) | $28 | In stock | |
| 10 mg | $88 | In stock | |
| 25 mg | $148 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
PD173074 is a potent, selective, ATP-competitive FGFR1 inhibitor with IC50 of ~25 nM.
PD173074 also inhibits autophosphorylation of VEGFR2 with IC50 of 100–200 nM.
PD173074 displays >1000-fold selectivity over Src, InsR, EGFR, PDGFR, etc.
| M.Wt | 523.6702 | |
| Formula | C28H41N7O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
DMSO: ≥ 52 mg/mL |
|
| Chemical Name/SMILES |
Urea, N-[2-[[4-(diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)- |
|
1. Mohammadi M, et al. EMBO J. 1998 Oct 15;17(20):5896-904.
2. Skaper SD, et al. J Neurochem. 2000 Oct;75(4):1520-7.
3. Nguyen PT, et al. Br J Cancer. 2013 Oct 15;109(8):2248-58.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
