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Chemical Structure : PD98059
CAS No.: 167869-21-8
Catalog No.: PC-42842Not For Human Use, Lab Use Only.
PD98059 (PD 098059) is a specific MEK inhibitor with IC50 of ~10 uM without significant inhibitory activity of MAPK.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $188 | In stock | |
| 50 mg | $278 | In stock | |
| 100 mg | $398 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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PD98059 (PD 098059) is a specific MEK inhibitor with IC50 of ~10 uM without significant inhibitory activity of MAPK.
PD98059 prevents activation of MAPK and subsequent phosphorylation of MAPK substrates both in vitro and in intact cells.
| M.Wt | 267.2793 | |
| Formula | C16H13NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 16 mg/mL; H2O: < 0.01 mg/mL |
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| Chemical Name/SMILES |
4H-1-Benzopyran-4-one, 2-(2-amino-3-methoxyphenyl)- |
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1. Dudley DT, et al. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7686-9.
2. Alessi DR, et al. J Biol Chem. 1995 Nov 17;270(46):27489-94.
3. Simon C, et al. Br J Cancer. 1999 Jul;80(9):1412-9.
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