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PDE10A-IN-32

Chemical Structure : PDE10A-IN-32

CAS No.: 1338795-39-3

PDE10A-IN-32

Catalog No.: PC-63306Not For Human Use, Lab Use Only.

PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM)..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM).

Physicochemical Properties

M.Wt 470.977
Formula C24H28ClFN6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine hydrochloride

References

1. Kadoh Y, et al. Chem Pharm Bull (Tokyo). 2018;66(3):243-250.

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