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Chemical Structure : PDE4D-IN-26b
Catalog No.: PC-63121Not For Human Use, Lab Use Only.
PDE4D-IN-26b is a potent, highly selective PDE4D inhibitor with IC50 of 0.6 nM, displays 75-fold lower activity against the PDE4A, B, and C subtypes, also exhibits 18,000-fold decreased potency against other PDE family members.
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PDE4D-IN-26b is a potent, highly selective PDE4D inhibitor with IC50 of 0.6 nM, displays 75-fold lower activity against the PDE4A, B, and C subtypes, also exhibits 18,000-fold decreased potency against other PDE family members; suppresses PDE4D-dependent malignant cell growth, but not in nonmalignant epithelial cells.
| M.Wt | 463.525 | |
| Formula | C28H27F2NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lin DC, et al. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6109-14.
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