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PDE6δ-IN-2

Chemical Structure : PDE6δ-IN-2

CAS No.: 2235358-31-1

PDE6δ-IN-2

Catalog No.: PC-25960Not For Human Use, Lab Use Only.

PDE6δ-IN-2 is a potent, small molecule PDE6δ (PDE6delta, PDE6D) inhibitor with KD of <30 nM in displacement assays, inibits binding of PDE6δ to farnesylated Ras proteins and inhibits oncogenic Ras signaling in cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PDE6δ-IN-2 is a potent, small molecule PDE6δ (PDE6delta, PDE6D) inhibitor with KD of <30 nM in displacement assays, inibits binding of PDE6δ to farnesylated Ras proteins and inhibits oncogenic Ras signaling in cells.

Physicochemical Properties

M.Wt 710.14
Formula C31H38BrClN4O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,4-Benzenedisulfonamide, N1-[(5-amino-2-bromophenyl)methyl]-N4-[(4-chlorophenyl)methyl]-N4-cyclopentyl-N1-(4-piperidinylmethyl)-

References

1. Patent WO2018130625 A1.

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