PDE6δ-IN-1

Chemical Structure : PDE6δ-IN-1

Catalog No.: PC-25959Not For Human Use, Lab Use Only.

PDE6δ-IN-1 is a potent, small molecule PDE6δ (PDE6delta, PDE6D) inhibitor with KD of <30 nM in displacement assays, inibits binding of PDE6δ to farnesylated Ras proteins and inhibits oncogenic Ras signaling in cells.

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Biological Activity

Physicochemical Properties

M.Wt	618.21
Formula	C29H36ClN5O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,4-Benzenedisulfonamide, N1-[(4-chlorophenyl)methyl]-N1-cyclopentyl-N4-(4-piperidinylmethyl)-N4-(2-pyrazinylmethyl)-

References

1. Patent WO2018130625 A1.

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PDE6δ-IN-1

Biological Activity

Physicochemical Properties

References

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