Chemical Structure : PELI1-IN-1
CAS No.: 3034889-94-3
Catalog No.: PC-26725Not For Human Use, Lab Use Only.
PELI1-IN-1 (PELI1 inhibitor 3d) is a specific small molecule inhibitor of E3 ubiquitin ligase Pellino-1 (PELI1) with binding Kd of 8.2 uM in fluorescence quenching assays, interrupts the interaction of PELI1 and SNAIL/SLUG.
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|---|---|---|---|
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
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| 100 mg | Get quote |
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PELI1-IN-1 (PELI1 inhibitor 3d) is a specific small molecule inhibitor of E3 ubiquitin ligase Pellino-1 (PELI1) with binding Kd of 8.2 uM in fluorescence quenching assays, interrupts the interaction of PELI1 and SNAIL/SLUG.
PELI1-IN-1 exhibits potent anti-TNBC activity against cell migration without affecting cell proliferation in vitro.
PELI1-IN-1 shows potent anti-TNBC metastasis efficacy without observable toxic side effects in vivo.
| M.Wt | 320.34 | |
| Formula | C20H16O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(E)-3'-(3,5-dihydroxystyryl)-[1,1'-biphenyl]-3,4'-diol |
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1. Guangsen Xu, et al. Eur J Med Chem. 2023 Dec 20:265:116060.

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