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Chemical Structure : PF-03715455
Catalog No.: PC-63103Not For Human Use, Lab Use Only.
PF-03715455 is a highly potent and selective inhibitor for p38α MAPK with IC50 of 1.6 nM.
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PF-03715455 is a highly potent and selective inhibitor for p38α MAPK with IC50 of 1.6 nM; shows efficacy and safety profiles as an inhaled agent for the treatment of COPD.
COPD
Phase 2 Discontinued
| M.Wt | 700.273 | |
| Formula | C35H34ClN7O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Millan DS, et al. J Med Chem. 2011 Nov 24;54(22):7797-814.
2. Singh D, et al. Eur J Clin Pharmacol. 2015 Oct;71(10):1175-84.
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