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Chemical Structure : PF-04418948
CAS No.: 1078166-57-0
Catalog No.: PC-45579Not For Human Use, Lab Use Only.
PF-04418948 (PF 04418948) is a novel potent and selective prostaglandin EP2 receptor antagonist.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $188 | In stock | |
| 50 mg | $348 | In stock | |
| 100 mg | $598 | In stock | |
| 250 mg | $988 | In stock | |
| 1 g | Get quote |
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PF-04418948 (PF 04418948) is a novel potent and selective, orally active prostaglandin EP2 receptor antagonist.
PF-04418948 inhibits prostaglandin E(2)(PGE(2))-induced increase in cAMP in cells with a functional K(B) value of 1.8 nM.
PF-04418948 attenuates the butaprost-induced cutaneous blood flow response in rats.
| M.Wt | 409.407 | |
| Formula | C23H20FNO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-Azetidinecarboxylic acid, 1-(4-fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]- |
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1. af Forselles KJ, et al. Br J Pharmacol. 2011 Dec;164(7):1847-56.
2. Birrell MA, et al. Br J Pharmacol. 2013 Jan;168(1):129-38.
3. Kach J, et al. J Biol Chem. 2014 Mar 14;289(11):7505-13.
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