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PF-04822163

Chemical Structure : PF-04822163

CAS No.: 1798334-07-2

PF-04822163 (PF 04822163;PF04822163)

Catalog No.: PC-61341Not For Human Use, Lab Use Only.

PF-04822163 is a potent and selective, CNS-penetrant PDE1 inhibitor with IC50 of 2.4 nM for PDE1B.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PF-04822163 is a potent and selective, CNS-penetrant PDE1 inhibitor with IC50 of 2.4 nM for PDE1B.

    Physicochemical Properties

    M.Wt 340.807
    Formula C19H17ClN2O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-4-(6-chloro-2,3-dihydro-1H-inden-1-yl)-7,8-dimethoxyquinazoline

    References

    1. Humphrey J, et al. Med Chem Commun, 5, 1290-1296.

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