Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : PF-05388169
Catalog No.: PC-61091Not For Human Use, Lab Use Only.
A potent, selective IRAK4 inhibitor with IC50 of 0.094 nM, >500-fold selectivity over IRAK1 (IC50=65 nM).
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A potent, selective IRAK4 inhibitor with IC50 of 0.094 nM, >500-fold selectivity over IRAK1 (IC50=65 nM); exhibits low nM potency in LPS- and R848-induced cytokine assays (IC50=85 nM) in human PBMCs; inhibits LPS-induced TNFα in an in vivo murine model.
| M.Wt | 391.427 | |
| Formula | C22H21N3O4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Lai CY, et al. J Immunol Res. 2017;2017:7807313.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
