Chemical Structure : PF-06649298
Catalog No.: PC-60604Not For Human Use, Lab Use Only.
PF-06649298 (PF06649298) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM.
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PF-06649298 (PF06649298) potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM; displays >60-fold selectvity over NaDC1 and NaDC3.
M.Wt | 294.347 | |
Formula | C16H22O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Pajor AM, et al. Mol Pharmacol. 2016 Dec;90(6):755-765.
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