Raxlaprazine Etomoxil (PF-06669571) | D1R agonist

Chemical Structure : PF-06669571

PF-06669571 (Raxlaprazine Etomoxil, PF-6669571)

Catalog No.: PC-62632Not For Human Use, Lab Use Only.

Raxlaprazine Etomoxil (PF-06669571, PF-6669571) is a novel dopamine D1 receptor (D1R) partial agonist with Ki of 10 nM, demonstrates efficacy in pre-clinical models of Parkinson’s disease symptoms.

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Biological Activity

Raxlaprazine Etomoxil (PF-06669571, PF-6669571) is a novel dopamine D1 receptor (D1R) partial agonist with Ki of 10 nM, demonstrates efficacy in pre-clinical models of Parkinson’s disease symptoms.

Physicochemical Properties

M.Wt	471.47
Formula	C23H36Cl2N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Urea, N′-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N-(ethoxymethyl)-N-methyl-

References

1. Gurrell R, et al. Clin Drug Investig. 2018 Feb 24. doi: 10.1007/s40261-018-0632-6.

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PF-06669571 (Raxlaprazine Etomoxil, PF-6669571)

Biological Activity

Physicochemical Properties

References

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