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Chemical Structure : PF-06678419
Catalog No.: PC-60603Not For Human Use, Lab Use Only.
PF-06678419 (PF06678419) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.44 uM.
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PF-06678419 (PF06678419) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.44 uM; displays relatively selectivity over NaDC1 and NaDC3 (7-10-fold).
| M.Wt | 364.135 | |
| Formula | C12H13IO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Pajor AM, et al. Mol Pharmacol. 2016 Dec;90(6):755-765.
2. Huard K, et al. Sci Rep. 2015 Dec 1;5:17391.
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