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Chemical Structure : PF 1022A
CAS No.: 133413-70-4
Catalog No.: PC-43003Not For Human Use, Lab Use Only.
PF1022A is an anthelmintic cyclodepsipeptide of fungal origin, binds to the latrophilin-like transmembrane receptor important for pharyngeal pumping in nematodes.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $380 | In stock | |
| 25 mg | $980 | In stock | |
| 100 mg | $1880 | In stock | |
| 250 mg | Get quote |
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PF1022A is an anthelmintic cyclodepsipeptide of fungal origin, binds to the latrophilin-like transmembrane receptor important for pharyngeal pumping in nematodes; binds to GABA receptors, which might contribute to the anthelmintic effect, like other cyclodepsipeptides, PF1022A acts as an ionophore.
| M.Wt | 949.1794 | |
| Formula | C52H76N4O12 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 43 mg/mL |
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| Chemical Name/SMILES |
Cyclo[(αR)-α-hydroxybenzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxybenzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl] |
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1. Sasaki T, et al. J Antibiot (Tokyo). 1992 May;45(5):692-7.
2. Dornetshuber R, et al. Biochem Pharmacol. 2009 Apr 15;77(8):1437-44.
3. Chen W, et al. Parasitol Res. 1996;82(2):97-101.
4. von Samson-Himmelstjerna G, et al. Parasitol Res. 2000 Mar;86(3):194-9.
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