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Chemical Structure : PI3Kβ inhibitor (P)-14
Catalog No.: PC-20468Not For Human Use, Lab Use Only.
PI3Kβ inhibitor (P)-14 is a potent, highly selective and orally bioavailable PI3Kβ inhibitor with IC50 of 2 nM.
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PI3Kβ inhibitor (P)-14 is a potent, highly selective and orally bioavailable PI3Kβ inhibitor with IC50 of 2 nM.
PI3Kβ inhibitor (P)-14 inhibits the phosphorylation of AKT (AKT1 ser473) in PTEN-deficient tumor cell lines with EC50 of 5-30 nM.
| M.Wt | 464.44 | |
| Formula | C25H14F2N8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Stephane Perreault, et al. ACS Med Chem Lett. 2020 Apr 13;11(6):1236-1243.
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