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PITCOIN2

Chemical Structure : PITCOIN2

CAS No.: 2397679-77-3

PITCOIN2 (LU-06-006)

Catalog No.: PC-20451Not For Human Use, Lab Use Only.

PITCOIN2 (LU-06-006) is a potent selective PI3KC2α inhibitor with IC50 of 126 nM, has selectivity against PI3KC2γ but shows micromolar activity on PI3KC2β.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PITCOIN2 (LU-06-006) is a potent selective PI3KC2α inhibitor with IC50 of 126 nM, has selectivity against PI3KC2γ but shows micromolar activity on PI3KC2β.

Physicochemical Properties

M.Wt 516.59
Formula C25H20N6O3S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-(3-hydroxyphenyl)thiazol-2-yl)-2-((4-oxo-3-phenethyl-3,4-dihydropteridin-2-yl)thio)acetamide

References

1. Lo WT, et al. Nat Chem Biol. 2023 Jan;19(1):18-27.

2. Patent WO2019234237 A1.

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