You are here:Home-Chemical Inhibitors & Agonists-Others-PHGDH-PKUMDL-WQ-2201
PKUMDL-WQ-2201

Chemical Structure : PKUMDL-WQ-2201

CAS No.: 592474-91-4

PKUMDL-WQ-2201 (WQ-2201)

Catalog No.: PC-72880Not For Human Use, Lab Use Only.

PKUMDL-WQ-2201 is a potent, selective, allosteric inhibitor of PHGDH, binds to allosteric site II.

Packing Price Stock Quantity
25 mg Get quote
100 mg Get quote
250 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PKUMDL-WQ-2201 is a potent, selective, allosteric inhibitor of PHGDH, binds to allosteric site II.
PKUMDL-WQ-2201 inhibited the serine biosynthesis pathway in cells, exhibited substantial inhibitory effects on MDA-MB-468 xenografts.

Physicochemical Properties

M.Wt 351.805
Formula C15H14ClN3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Chloro-4-[5-[(ethylcarbamothioylhydrazinylidene)methyl]furan-2-yl]benzoic acid

References

1. Qian Wang, et al. Cell Chem Biol. 2017 Jan 19;24(1):55-65.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: