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Chemical Structure : PNU-112455A
CAS No.: 21886-12-4
Catalog No.: PC-62677Not For Human Use, Lab Use Only.
PNU-112455A is an ATP-competitive CDK2/5 inhibitor with Ki of 2 uM and 2 uM for cdk2·GST-cyclin E and cdk5·GST-p25 respectively, shows no activity against c-Met, IGR-1R, and ERK2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | Get quote | ||
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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PNU-112455A is an ATP-competitive CDK2/5 inhibitor with Ki of 2 uM and 2 uM for cdk2·GST-cyclin E and cdk5·GST-p25 respectively, shows no activity against c-Met, IGR-1R, and ERK2.
| M.Wt | 301.749 | |
| Formula | C10H12ClN5O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N4-(6-aminopyrimidin-4-yl)-sulfanilamide hydrochloride |
|
1. Clare PM, et al. J Biol Chem. 2001 Dec 21;276(51):48292-9.
2. Monaco EA 3rd, et al. Biochem Pharmacol. 2004 May 15;67(10):1947-64.
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