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Chemical Structure : PNU-159682
CAS No.: 202350-68-3
Catalog No.: PC-45045Not For Human Use, Lab Use Only.
A highly potent metabolite of the anthracycline nemorubicin with outstanding cytotoxicity.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $760 | In stock | |
| 10 mg | $1280 | In stock | |
| 50 mg | $4000 | In stock |
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A highly potent metabolite of the anthracycline nemorubicin with outstanding cytotoxicity; a topoisomerase inhibitor and ADCs cytotoxin.
| M.Wt | 641.6192 | |
| Formula | C32H35NO13 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-, (8S,10S)- |
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1. Quintieri L, et al. Clin Cancer Res. 2005 Feb 15;11(4):1608-17.
2. Yu SF, et al. Clin Cancer Res. 2015 Jul 15;21(14):3298-306.
3. Mazzini S, et al. Bioorg Med Chem. 2012 Dec 15;20(24):6979-88.
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