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Chemical Structure : PPTN hydrochloride
CAS No.: 1992047-65-0
Catalog No.: PC-22103Not For Human Use, Lab Use Only.
PPTN hydrochloride is a potent, highly specific antagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
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| 100 mg | Get quote |
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PPTN hydrochloride is a potent, highly specific antagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays.
PPTN exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors at 1 uM.
PPTN inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.
| M.Wt | 511.97 | |
| Formula | C29H25ClF3NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Naphthalenecarboxylic acid, 4-[4-(4-piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-, hydrochloride (1:1) |
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1. Yu J, et al. J Med Chem. 2018 May 16. doi: 10.1021/acs.jmedchem.8b00168.
2. Junker A, et al. J Med Chem. 2016 Jul 14;59(13):6149-68.
3. Barrett MO, et al. Mol Pharmacol. 2013 Jul;84(1):41-9.
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