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Chemical Structure : PRT-060318
CAS No.: 1194961-19-7
Catalog No.: PC-43303Not For Human Use, Lab Use Only.
PRT-060318 is a potent and selective Syk inhibitor with IC50 of 4 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $138 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $368 | In stock | |
| 100 mg | Get quote |
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PRT-060318 is a potent and selective Syk inhibitor with IC50 of 4 nM.
PRT-060318 shows selectivity in a broad panel of kinase enzyme assays.
PRT-060318 completely inhibits Heparin-induced thrombocytopenia (HIT) immune complex-induced aggregation of both human and transgenic HIT mouse platelet.
| M.Wt | 340.4228 | |
| Formula | C18H24N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 5.6 mg/mL |
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| Chemical Name/SMILES |
5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(3-methylphenyl)amino]- |
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1. Reilly MP, et al. Blood. 2011 Feb 17;117(7):2241-6.
2. Hoellenriegel J, et al. Leukemia. 2012 Jul;26(7):1576-83.
3. Andre P, et al. Blood. 2011 Nov 3;118(18):5000-10.
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