 
                Chemical Structure : PRT4165
CAS No.: 31083-55-3
Catalog No.: PC-45731Not For Human Use, Lab Use Only.
PRT4165 (NSC 600157) is a potent inhibitor of PRC1-mediated H2A ubiquitylation, inhibits the E3 ubiquitin ligase activity of PRC1, but not RNF8.
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	PRT4165 (NSC 600157) is a potent inhibitor of PRC1-mediated H2A ubiquitylation, inhibits the E3 ubiquitin ligase activity of PRC1, but not RNF8.
	PRT-4165 inhibits double-strand breaks (DSBs) repair.
| M.Wt | 235.2375 | |
| Formula | C15H9NO2 | |
| Appearance | Solid | |
| Storage | 
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| Solubility | 10 mM in DMSO | |
| Chemical Name/SMILES | 1H-Indene-1,3(2H)-dione, 2-(3-pyridinylmethylene)- | |
1. Ismail IH, et al. J Biol Chem. 2013 Sep 13;288(37):26944-54.

 
                 
                 
                 
                 
                 
                 
                 
                 
            
            
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