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Chemical Structure : PSB-0739
Catalog No.: PC-21206Not For Human Use, Lab Use Only.
PSB-0739 is a high potent, non-nucleotide-derived competitive antagonist of platelet P2Y12 receptor with Ki of 24.9 nM.
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PSB-0739 is a high potent, non-nucleotide-derived competitive antagonist of platelet P2Y12 receptor with Ki of 24.9 nM.
PSB-0739 is a potent competitive non-nucleotide antagonist at the human P2Y12 receptor with a pA2 value of 9.8.
PSB-0739 inhibits ADP-evoked Ca2+ responses with an EC50 of 5.4±1.8 μM and causes a rightward parallel shift in the ADP concentration–response curve in THP-1 cells.
| M.Wt | 609.53 | |
| Formula | C26H17N3Na2O8S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Baqi Y, et al. J Med Chem. 2009 Jun 25;52(12):3784-93.
2. Hoffmann K, et al. J Pharmacol Exp Ther. 2009 Nov;331(2):648-55.
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