PSB-15417 | P2X4 antagonist | Probechem Biochemicals

Chemical Structure : PSB-15417

PSB-15417 (PSB15417)

Catalog No.: PC-26162Not For Human Use, Lab Use Only.

PSB-15417 is a potent, specific P2X4 receptor (P2X4R) antagonist with IC50 of 21.9 nM and 37 nM for human and rat P2X4 receptor, shows limited activity against P2X1, P2X2, P2X3 and P2X7 receptors (All IC50>2 uM).

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Biological Activity

Physicochemical Properties

M.Wt	362.45
Formula	C20H18N4OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(1H-indol-3-yl)-2-((2-methyl-5-(3-methyl-1,2,4-thiadiazol-5-yl)phenyl)amino)ethan-1-one

References

1. Müller C. E.et al. Purinergic Signal. 2021, 17, 633–648.

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PSB-15417 (PSB15417)

Biological Activity

Physicochemical Properties

References

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