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PSB-16434

Chemical Structure : PSB-16434

CAS No.: 2189700-02-3

PSB-16434 (PSB16434)

Catalog No.: PC-21649Not For Human Use, Lab Use Only.

PSB-16434 is a highly potent, Gi pathway-selective GPR84 agonist with cAMP EC50 of 7.1 nM, 79-fold selective over β-arrestin-2 recruitment activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PSB-16434 is a highly potent, Gi pathway-selective GPR84 agonist with cAMP EC50 of 7.1 nM, 79-fold selective over β-arrestin-2 recruitment activity.
PSB-16434 shows selectivity over other free fatty acid-activated receptors.

Physicochemical Properties

M.Wt 265.70
Formula C12H12ClN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-((4-chlorophenethyl)amino)pyrimidine-2,4(1H,3H)-dione

References

1. Thanigaimalai Pillaiyar, et al. ACS Omega. 2018 Mar 31;3(3):3365-3383.

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