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PSB-2001

Chemical Structure : PSB-2001

CAS No.: 978-62-1

PSB-2001 (PSB2001, IMD0354)

Catalog No.: PC-26165Not For Human Use, Lab Use Only.

PSB-2001 is a potent, selective and competitive P2X1 receptor (P2X1R) with IC50 of 19.2 nM, weakly inhibits P2X4, P2X7 and shows no activity against P2X2, P2X3 receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PSB-2001 is a potent, selective and competitive P2X1 receptor (P2X1R) with IC50 of 19.2 nM, weakly inhibits P2X4, P2X7 and shows no activity against P2X2, P2X3 receptors.

Physicochemical Properties

M.Wt 383.67
Formula C15H8ClF6NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide

References

1. Maoqun Tian, et al. J Med Chem. 2020 Jun 11;63(11):6164-6178.

2. Christa E Müller, et al. Recommended tool compounds and drugs for blocking P2X and P2Y receptors. Purinergic Signal. 2021 Dec;17(4):633-648.

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