PSB-OR-2020

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Chemical Structure : PSB-OR-2020

Catalog No.: PC-26169Not For Human Use, Lab Use Only.

PSB-OR-2020 is a potent, selective P2X4 receptor antagonist, inhibits ATP-induced Ca2+ influx by in 1321N1 astrocytoma cells stably transfected with the human P2X4 receptor with IC50 of 6.32 nM, >300-fold selective over P2X1, P2X2, P2X3, and P2X7.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	438.55
Formula	C23H26N4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-(4-(1,2-dihydroxypropane-2yl)indolin-1-yl)-2-((2-methyl-5-(3-methyl-1,2,4-thiadiazol-5-yl)phenyl)amino)ethane-1-one

References

1. Nagel J, et al. Purinergic Signal. 2024 Dec;20(6):645-656.

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PSB-OR-2020

Biological Activity

Physicochemical Properties

References

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