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PSI-421

Chemical Structure : PSI-421

CAS No.: 1067186-56-4

PSI-421 (PSI 421;PSI421)

Catalog No.: PC-61287Not For Human Use, Lab Use Only.

PSI-421 is a potent, orally bioavailable P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PSI-421 is a potent, orally bioavailable P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury.

Physicochemical Properties

M.Wt 407.773
Formula C20H13ClF3NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid

References

1. Huang A, et al. J Med Chem. 2010 Aug 26;53(16):6003-17.

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