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Chemical Structure : PSN632408
CAS No.: 857652-30-3
Catalog No.: PC-20444Not For Human Use, Lab Use Only.
PSN632408 (PSN 632408) is a selective small-molecule GPR119 agonist with cAMP EC50 of 7.9 and 5.6 uM for mouse and human GPR119 receptor, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $228 | In stock | |
| 100 mg | $498 | In stock | |
| 200 mg | $758 | In stock | |
| 1 g | Get quote |
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PSN632408 (PSN 632408) is a selective small-molecule GPR119 agonist with cAMP EC50 of 7.9 and 5.6 uM for mouse and human GPR119 receptor, respectively.
PSN632408 is selective for GPR119, shows no acitvities against cannabinoid receptors CB1 and CB2, PPARα, PPARγ, as well as a set of 107 targets comprising GPCRs, ligand-gated ion channels, other receptors.
PSN632408 (30-100 mg/kg, i.p.) acutely reduce food intake in freely feeding male Sprague-Dawley rats, did not significantly alter locomotor activity.
PSN632408 (100 mg, Oral) reduces body weight gain and white adipose tissue deposition upon subchronic oral administration to high-fat-fed rats.
| M.Wt | 360.41 | |
| Formula | C18H24N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
tert-butyl 4-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methoxy)piperidine-1-carboxylate |
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1. Overton HA,, et al. Cell Metab. 2006 Mar;3(3):167-75.
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