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Chemical Structure : PTK7/β-catenin inhibitor 01065
Catalog No.: PC-38652Not For Human Use, Lab Use Only.
PTK7/β-catenin inhibitor 01065 is a small molecule inhibitor of PTK7/β-catenin interaction (IC50=8.9 uM) targeting the Wnt pathway signaling, induces antiproliferative and antitumor effects in vitro in CRC cells harboring β-catenin or adenomatous polyposis coli (APC) mutations.
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PTK7/β-catenin inhibitor 01065 is a small molecule inhibitor of PTK7/β-catenin interaction (IC50=8.9 uM) targeting the Wnt pathway signaling, induces antiproliferative and antitumor effects in vitro in CRC cells harboring β-catenin or adenomatous polyposis coli (APC) mutations.
| M.Wt | 340.382 | |
| Formula | C22H16N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ganier L, et al. ACS Chem Biol. 2022 Apr 28. doi: 10.1021/acschembio.1c00826.
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