Chemical Structure : Parthenolide
CAS No.: 20554-84-1
Catalog No.: PC-25411Not For Human Use, Lab Use Only.
Parthenolide is a sesquiterpene lactone found in the medicinal herb Feverfew, exhibits anti-inflammatory activity by inhibiting NF-κB activation, impairs breast cancer cell proliferation via inhibitiong USP10, also inhibits HDAC1 protein without affecting other class I/II HDACs.
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Parthenolide is a sesquiterpene lactone found in the medicinal herb Feverfew, exhibits anti-inflammatory activity by inhibiting NF-κB activation, impairs breast cancer cell proliferation via inhibitiong USP10, also inhibits HDAC1 protein without affecting other class I/II HDACs.
M.Wt | 248.32 | |
Formula | C15H20O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(3aS,9aR,10aR,10bS,E)-6,9a-Dimethyl-3-methylene-3a,4,5,8,9,9a,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-2(3H)-one |
1. Zhao WS, et al. Acta Pharmacol Sin. 2023 Aug;44(8):1701-1711.
2. Nakshatri H, et al. Cell Death Dis. 2015 Jan 22;6:e1608.
3. Zhao X, et al. J Exp Clin Cancer Res. 2014 Jan 6;33:3.
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