Pevifoscorvir | HBV capsid modulator | Probechem Biochemicals

Chemical Structure : Pevifoscorvir

Pevifoscorvir (ALG-000184 free base)

Catalog No.: PC-27491Not For Human Use, Lab Use Only.

Pevifoscorvir (ALG-000184 free base) is a highly soluble prodrug of the potent HBV capsid assembly modulator (CAM) ALG-001075 (HepG2.117, EC50=0.63 nM).

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Biological Activity

Pevifoscorvir (ALG-000184 free base) is a highly soluble prodrug of the potent HBV capsid assembly modulator (CAM) ALG-001075 (HepG2.117, EC50=0.63 nM).

Physicochemical Properties

M.Wt	532.42
Formula	C23H22FN4O8P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Pyrrole-3-acetamide, 5-[[(3-cyano-4-fluorophenyl)amino]carbonyl]-N-(3-ethynyl-3-oxetanyl)-1,2,4-trimethyl-α-oxo-N-[(phosphonooxy)methyl]-

References

1. Vendeville S, et al. J Med Chem. 2024 Dec 12;67(23):21126-21142.

2. Gane E, et al. Antivir Ther. 2025 Dec;30(6):13596535251392955.

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Pevifoscorvir (ALG-000184 free base)

Biological Activity

Physicochemical Properties

References

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