Catalog No.: PC-24495Not For Human Use, Lab Use Only.
Pirfenidone (AMR69) is an antifibrotic agent and TGF-β inhibitor, attenuates CCL2 and CCL12 production in fibrocyte cells, shows growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines.
Pirfenidone (AMR69) is an antifibrotic agent and TGF-β inhibitor, attenuates CCL2 and CCL12 production in fibrocyte cells, shows growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines.
Physicochemical Properties
M.Wt
185.23
Formula
C12H11NO
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
5-Methyl-1-phenylpyridin-2(1H)-one
References
1. Taniyama M, et al. Eur J Clin Pharmacol. 1997;52(1):77-8.
2. Lee BS, et al. J Clin Endocrinol Metab. 1998 Jan;83(1):219-23.
3. Silva TA, et al. Int J Mol Sci. 2024 Jul 3;25(13):7302.
4. Burghardt I, et al. Biochem Biophys Res Commun. 2007 Mar 9;354(2):542-7.
