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Chemical Structure : Pluripotin
CAS No.: 839707-37-8
Catalog No.: PC-42663Not For Human Use, Lab Use Only.
A small molecule that can maintain the self-renewal of mESC (murine embryonic stem cells) in the absence of feeder cells and exogenous factors.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $72 | In stock | |
| 10 mg | $120 | In stock | |
| 25 mg | $200 | In stock | |
| 50 mg | Get quote |
Bulk size, bulk discount!
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A small molecule that can maintain the self-renewal of mESC (murine embryonic stem cells) in the absence of feeder cells and exogenous factors; works through dual inhibition of RasGAP and ERK1; maintains the undifferentiated phenotype of mES cells with EC50 of 1 uM, and shows low cellular toxicity (>30 uM).
| M.Wt | 550.535 | |
| Formula | C27H25F3N8O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 33 mg/mL |
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| Chemical Name/SMILES |
Benzamide, N-[3-[7-[(1,3-dimethyl-1H-pyrazol-5-yl)amino]-1,4-dihydro-1-methyl-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)- |
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1. Chen S, et al. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17266-71.
2. Yang W, et al. Stem Cells. 2009 Feb;27(2):383-9.
3. Pieters T, et al. Stem Cell Rev. 2012 Sep;8(3):768-78.
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