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Chemical Structure : Polatuzumab
CAS No.:
Catalog No.: PC-Ab1112Not For Human Use, Lab Use Only.
Polatuzumab (Anti-human CD79b) is a human CD79b mAb, component of antibody-drug conjugate (ADC) Polatuzumab vedotin. Polatuzumab is internalized, cleaved by lysosomal proteases, thereby delivering MMAE to malignant B-cells. The released MMAE binds to microtubules and kills dividing cells by inhibiting cell division and inducing apoptosis. CD79B is a subunit of the heterodimer B-cell receptor Igα/Igβ (CD79A/CD79B), also known as B29, Ig beta and B cell antigen receptor complex-associated protein
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $358 | In stock | |
| 5 mg | $758 | In stock | |
| 10 mg | $1280 | In stock | |
| 100 mg | Get quote |
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Polatuzumab (Anti-human CD79b) is a human CD79b mAb, component of antibody-drug conjugate (ADC) Polatuzumab vedotin. Polatuzumab is internalized, cleaved by lysosomal proteases, thereby delivering MMAE to malignant B-cells. The released MMAE binds to microtubules and kills dividing cells by inhibiting cell division and inducing apoptosis. CD79B is a subunit of the heterodimer B-cell receptor Igα/Igβ (CD79A/CD79B), also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain.
| M.Wt | ||
| Formula | Human IgG1-Kappa | |
| Appearance | Solid | |
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| Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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